Oral HPV Infection Is Common
SUMMARY AND COMMENT
Such infection — associated with a form of oropharyngeal squamous cell carcinoma — is present in 6.9% of the U.S. population aged 14 to 69.
Reviewing:
Gillison ML et al., JAMA 2012 Jan 26
Cytomegalovirus Serostatus and Outcome in Critically Ill Patients
SUMMARY AND COMMENT
February 1, 2012
Thomas Glück, MD
In a large, retrospective study, 64% of critically ill patients were CMV positive, but CMV serostatus was not associated with outcome.
Reviewing:
De Vlieger G et al., Crit Care Med 2012 Jan; 40:36
Global Burden of Infant Group B Streptococcal Disease
SUMMARY AND COMMENT
In a meta-analysis of global data, incidence and fatality rates differed among countries, but the underlying serotypes were similar.
Reviewing:
Edmond KM et al., Lancet 2012 Jan 5
In-Feed Antibiotics and the Swine Intestinal Microbiome: Unintended Consequences
SUMMARY AND COMMENT
Just 14 days of low-dose oral antibiotics markedly increased the diversity and abundance of antibiotic-resistance genes.
Reviewing:
Looft T et al., Proc Natl Acad Sci U S A 2012 Jan 17
Nosocomial Measles Outbreak
SUMMARY AND COMMENT
Measles, contracted in a hospital emergency department, affected both unimmunized and previously vaccinated individuals.
Reviewing:
Centers for Disease Control and Prevention (CDC)., MMWR Morb Mortal Wkly Rep 2012 Jan 20; 61:30
A Novel Cause of Food Poisoning — Something's Fishy
SUMMARY AND COMMENT
A recently described marine parasite, acquired through ingestion of raw fish, was identified as the cause of several foodborne illness outbreaks in Japan.
Reviewing:
Kawai T et al., Clin Infect Dis 2012 Jan 26
Clean Your Scope!
SUMMARY AND COMMENT
Stethoscopes can readily transfer both Clostridium difficile and methicillin-resistant Staphylococcus aureus.
Reviewing:
Vajravelu RK et al., Infect Control Hosp Epidemiol 2012 Jan; 33:96
Influenza in Neurologically Compromised Patients
SUMMARY AND COMMENT
An outbreak of influenza in patients with incapacitating neurological conditions caused severe infection, despite immunization.
Reviewing:
Centers for Disease Control and Prevention (CDC)., MMWR Morb Mortal Wkly Rep 2012 Jan 6; 60:1729
Conjugate Vaccines Reduce Incidence of Antibiotic-Nonsusceptible IPD
SUMMARY AND COMMENT
Incidence was markedly lower in 2007–2008 than in 1998–1999, before introduction of the 7-valent pneumococcal conjugate vaccine.
Reviewing:
Hampton LM et al., J Infect Dis 2012 Feb 1; 205:401
Preventing Serogroup B Meningococcal Disease
SUMMARY AND COMMENT
In a phase IIB/III study conducted among adolescents in Chile, a multicomponent vaccine — 4CMenB — was immunogenic and safe.
Reviewing:
Santolaya ME et al., Lancet 2012 Jan 18
Stephens DS., Lancet 2012 Jan 18